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. 2020 Apr 3;18:57. doi: 10.1186/s12951-020-00612-7

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — a The distribution of DiR labelled BTZ-NP in tumor bearing mouse measured by near-infrared fluorescence imaging (the black circle indicates the tumor tissue); b The ICP-MS results of the boron element distribution in the main organs and the tumors (* indicates statistically different, p < 0.05); c The tumor growth profiles (* indicates statistically different, p < 0.05); d The statistic results of the tumor weights at the end of the experiment (* indicates statistically different, p < 0.05); e The body weight curves; f The picture of the tumor tissues at the end of the experiment (the circle implies no tumor tissue observed); g IHC staining of the tumor tissues (the scale bar represents 50 µm)