Table 1.
Diagnostic value of US and USE for the diagnostic of malignant thyroid nodules
| Criteria | Benign | Malignant | Sensitivity (%) | Specificity (%) | Accuracy (%) | PPV (%) | NPV (%) | P |
|---|---|---|---|---|---|---|---|---|
| Microcalcification | ||||||||
| Yes | 211 | 416 | 49.9 | 65.6 | 56.4 | 66.3 | 48.9 | <0.01 |
| no | 400 | 318 | ||||||
| Taller than wide | ||||||||
| yes | 55 | 309 | 37.1 | 91.0 | 59.8 | 84.9 | 51.4 | <0.01 |
| no | 556 | 525 | ||||||
| Irregular margins | ||||||||
| Yes | 525 | 83 | 93.9 | 14.1 | 60.1 | 59.9 | 62.8 | <0.01 |
| no | 86 | 51 | ||||||
| ETE | ||||||||
| Yes | 469 | 693 | 83.0 | 23.2 | 57.7 | 59.6 | 50.0 | <0.01 |
| No | 142 | 141 | ||||||
| Disrupted rim calcification | ||||||||
| Yes | 7 | 39 | 4.7 | 98.9 | 44.4 | 84.8 | 43.2 | <0.01 |
| No | 604 | 795 | ||||||
| Kwak’s TI-RADS | ||||||||
| 4a | 5 | 2 | 62.2 | 70.2 | 65.6 | 74.0 | 57.7 | <0.01 |
| 4b | 424 | 313 | ||||||
| 4c | 182 | 367 | ||||||
| 5 | 0 | 152 | ||||||
| Elasticity score | ||||||||
| > 3 | 240 | 771 | 92.4 | 60.7 | 79.0 | 76.3 | 85.5 | <0.01 |
| ≤ 3 | 371 | 63 | ||||||
| SR value | ||||||||
| > 2.99 | 305 | 676 | 81.1 | 50.1 | 68.9 | 65.9 | 67.9 | <0.01 |
| ≤ 2.99 | 306 | 158 | ||||||
PPV positive predictive value, NPV negative predictive value, ETE Extrathyroidal extension, TI-RADS Thyroid Imaging Reporting and Data System, SR strain ratio