Table 3.
Yusuf criteria on quality of subgroup analyses (for cluster randomized controlled trials (CRTs) and randomized controlled trials (RCTs) with subgroup analysis)
Yusuf criteria | Cluster RCTs N = 25 |
Individual RCTs N = 49 |
Total N = 74 |
---|---|---|---|
(%) | (%) | N (%) | |
Subgroup analysis pretested or planned a priori to the study commencement | 68 | 67 | 50 (68) |
Hypothesis or rationale for the analysis provided | 60 | 61 | 45 (61) |
Statistical test for interaction performed between the subgroups | 80 | 70 | 54 (73) |
Overall treatment results emphasized more than the findings of the subgroup analysis | 64 | 73 | 52 (70) |