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. 2020 Apr 3;21:308. doi: 10.1186/s13063-020-4223-5

Table 3.

Yusuf criteria on quality of subgroup analyses (for cluster randomized controlled trials (CRTs) and randomized controlled trials (RCTs) with subgroup analysis)

Yusuf criteria Cluster RCTs
N = 25
Individual RCTs
N = 49
Total
N = 74
(%) (%) N (%)
Subgroup analysis pretested or planned a priori to the study commencement 68 67 50 (68)
Hypothesis or rationale for the analysis provided 60 61 45 (61)
Statistical test for interaction performed between the subgroups 80 70 54 (73)
Overall treatment results emphasized more than the findings of the subgroup analysis 64 73 52 (70)