Scheme 5.
Reagents and conditions: (a) CH3OH, HCl; (b) NBS, CHCl3, BzooBz; (c) n-BuLi, THF, −78 °C; (d) Pd-C, H2, THF; (e) 3,5-dimethoxybenzoyl chloride, pyridine, 25 °C; (f) LiOH, THF/CH3OH/H2O = 3:1:1, 25 °C.
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