Table 3.
Effect of compounds 16b, 16h, 16k, 18l, and CsA on the proliferation of mouse spleen cells induced by Con A in vitro
| Dose (μM) | Inhibitory rate (%)a |
||||
|---|---|---|---|---|---|
| CsA | 16b | 16h | 16k | 18g | |
| 100 | 84.31 ± 4.88b | 47.35 ± 4.98b | 46.74 ± 5.39b | 49.05 ± 4.69b | 28.83 ± 3.39b |
| 10 | 82.57 ± 5.20b | 29.78 ± 5.00 | 34.26 ± 5.60b | 22.71 ± 7.06 | 7.46 ± 4.13 |
| 1 | 56.52 ± 1.60 | 14.13 ± 9.97 | 20.76 ± 8.41 | 15.33 ± 7.81 | 1.20 ± 6.41 |
a
Each value indicates the mean ± SD of three experiments using three mice with triplicate sets in each assay.
b
One-way analysis of variance revealed a significant effect at P < 0.05.