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. 2014 Feb 6;104:118–127. doi: 10.1016/j.antiviral.2014.01.021

Fig. 3.

Fig. 3

Viral expression was rescued in RNase L knockdown cells. (A) HepG2-NTCP cells transfected in suspension with siRNAs (50 nM) were plated and infected on the following day with HBV. The cells were further transfected 16 h later with p2–5A (100 μM) or poly(I:C) (100 ng/well). Viral pgRNA at 9 days post-infection was quantified by RT-qPCR (∗P < 0.05). (B) The knockdown efficiency of RNase L was determined by real-time PCR.