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Hyaluronan-induced fast-proliferative PDMSC had lower mitochondrial biogenesis. (A) Mitochondrial mass; (B) mtDNA copy number; All data is expressed as mean±SD of at least three replicates and analyzed by the paired t-test (*p<0.05, **p<0.01). Mitochondrial mass was analyzed by using PDMSCs transfected with expression plasmid pAS3w-DsRed2-mito. SHA: medium supplemented hyaluronan, CHA: coated hyaluronan, mtDNA: mitochondrial DNA, RFU: relative fluorescence unit.
