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. 2020 Mar 27;19:1533033820905825. doi: 10.1177/1533033820905825

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© The Author(s) 2020

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — SOX5 upregulation overcomes miR-338-3p-mediated disruptions to Wnt/β-catenin signaling. A, B, How miR-338-3p or SOX5 influenced nuclear β-catenin, c-myc, and cyclin D1 levels were assessed via Western blotting. C, D, The TOP/FOP luciferase assay was utilized as a means of assessing how miR-338-3p and SOX5 influenced Wnt/β-catenin signaling. *P < .05, **P < .01, ***P < .001.