Table 2.
Univariate and Multivariate Cox Regression Analyses of Overall Survival and Disease-Free Survival in Patients With Gastric Cancer.
| Variables | Univariate Analyses | Multivariate Analyses | ||||
|---|---|---|---|---|---|---|
| Hazard Ratio | 95% CI | P | Hazard Ratio | 95% CI | P | |
| Overall survival | ||||||
| Age (years): ≥60/<60 | 0.635 | 0.389-2.928 | .426 | – | – | – |
| Gender: Male/female | 0.542 | 0.331-1.387 | .329 | – | – | – |
| Tumor diameter (cm): ≥5/<5 | 2.876 | 1.235-3.254 | .017 | 1.347 | 1.152-2.364 | .019 |
| Differentiation grade: Poor+ moderate/well | 3.562 | 1.206-4.159 | .022 | 2.611 | 1.145-3.152 | .025 |
| TNM stage: III/I + II | 2.184 | 1.635-3.212 | .031 | 2.826 | 1.256-2.807 | .045 |
| Lymph node metastasis: Yes/no | 3.375 | 2.317-4.059 | .032 | 3.104 | 1.879-3.624 | .043 |
| MiR-338-3p level: Low/high | 2.392 | 1.761-3.569 | .007 | 2.217 | 1.695-2.798 | .021 |
| Recurrence-free survival | ||||||
| Age (years): ≥ 60/<60 | 0.667 | 0.325-3.928 | 0.388 | – | – | – |
| Gender: Male/female | 0.947 | 0.439-1.307 | .429 | – | – | – |
| Tumor diameter (cm): ≥5/<5 | 2.643 | 1.985-3.568 | .032 | 2.162 | 1.297-3.714 | .042 |
| Differentiation grade: Poor + moderate/well | 3.246 | 1.761-3.527 | .032 | 2.754 | 1.451-3.245 | .041 |
| TNM stage: III/I + II | 3.134 | 1.756-3.975 | .022 | 2.788 | 1.984-3.884 | .035 |
| Lymph node metastasis: Yes/no | 3.563 | 1.716-4.112 | .031 | 2.109 | 1.325-3.754 | .043 |
| MiR-338-3p level: Low/high | 2.574 | 1.172-4.319 | .011 | 2.501 | 1.265-3.801 | .019 |
Abbreviations: HR, hazard ratio; 95% CI, 95% confidence interval.