Table 1.
Histopathological analysis of livers.
| Sample name | Inflammationa | Steatosisb | Hepatocellular necrosisc | Histological score (0–9) |
|---|---|---|---|---|
| Cnot1-LKO 1 | 3 | 0 | 3 | 6 |
| Cnot1-LKO 2 | 3 | 0 | 3 | 6 |
| Cnot1 (fl/fl) 1 | 0 | 0 | 0 | 0 |
| Cnot1 (fl/fl) 2 | 0 | 0 | 0 | 0 |
| Alb-CreERT2 1 | 0 | 1 | 0 | 1 |
| Alb-CreERT2 2 | 0 | 0 | 0 | 0 |
a
0, no inflammation; 1, mild lymphocytic infiltration in the portal triad; 2, severe lymphocytic infiltration in portal triad; 3, extended infiltration of lymphocytes throughout the liver.
b
0, no steatosis; 1, microsteatosis; 2, microsteatosis and mild macrosteatosis; 3, severe macrosteatosis.
c
0, no necrosis; 1, mild necrosis; 2, moderate necrosis; 3, severe necrosis.