| Methods |
RCT |
| Participants |
20 adults, (15 males, 5 females) admitted to a burn centre in China from July 1998 to July 1999. Mean age: 30.5 years; intervention group mean age: 32 years (SD = 4); control group mean age: 29 years (SD = 6). Mean 61% TBSA, mean 27% third‐degree TBSA. All participants underwent eschar excision < 4 days and skin autografting. |
| Interventions |
rhGH 0.5 IU/kg/day subcutaneously (n = 10) or normal saline subcutaneously from the 3rd to 17th post‐burn day |
| Outcomes |
Healing time of deep partial‐thickness burns and donor sites in days. Wound healing rate was not defined. Length of hospital stay in days. Hyperglycaemia (blood sugar > 12 mmol/L for 3 consecutive days). Mortality was zero in both groups, therefore these data with no events were not used in this meta‐analysis. |
| Funding |
|
| Notes |
Article in Chinese |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
Method of randomisation not reported |
| Allocation concealment (selection bias) |
Unclear risk |
Not reported |
| Blinding (performance bias and detection bias)
All outcomes |
Unclear risk |
Not reported |
| Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
No missing data for the healing times of burn wounds and donor sites and duration of hospital stay |
| Selective reporting (reporting bias) |
Low risk |
All presented outcome data were pre‐specified, but the study protocol was not available |
