Sun 1998.

Methods	Placebo‐controlled prospective study
Participants	16 adults (age range: 19 to 50 years) admitted to a burn centre in China between February 1996 and June 1997. Mean 81% TBSA; mean 61% third‐degree TBSA. All participants underwent eschar excision < 4 days and autografting with skin pulp. participants with associated injuries were excluded.
Interventions	rhGH 0.3 IU/kg/day subcutaneously (n = 8) or 2 cc normal saline (n = 8) for 10 days, starting on the first postoperative day
Outcomes	Grafted burn wound area and donor site healing time. Healing time was not defined. Wound healing rate at the 30th postoperative day. Duration of hospitalisation. Serum amino acid profile on Days 1 and 20 post‐burn. The hyperglycaemia incidence was zero in both groups; therefore, these data with no events were not used in this meta‐analysis.
Funding
Notes	Article in Chinese
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Method of randomisation not reported
Allocation concealment (selection bias)	Unclear risk	Not reported
Blinding (performance bias and detection bias) All outcomes	Unclear risk	Not reported
Incomplete outcome data (attrition bias) All outcomes	Low risk	No missing data for the healing time of burn wounds or donor sites and the duration of hospital stay
Selective reporting (reporting bias)	High risk	Mortality and septicaemia were not pre‐specified outcomes. No study protocol was available.

IGF‐1: insulin‐like growth factor‐1; IU: international units; RCT: randomised controlled trial; rhGH: recombinant human growth hormone; SD: standard deviation; TBSA: total body surface area