Table 2.
Absolute numbers of activated bystander and donor lymphocytes isolated from the brains of TCLi mice
| Naive TCLi (n=3) | Experimental group (TCLi mice+MHV) |
|||
|---|---|---|---|---|
| MHV only (n=5) | hCLIP85:CFA (n=4) | Undepleted B6.PLa (n=8) | ||
| CD4+/IFN-γ+/Thy 1.1+b | NA | NA | NA | 1.0±0.2×104 |
| CD4+/IFN-γ+/Thy 1.2+b | 0.5±0.5×102 | 2.5±1.6×102 | 5.9±1.4×103c | 2.7±1.5×102 |
a
Donor population.
b
Absolute number of activated T cells calculated as described in Section 2 ±S.E. per brain.
c
The number of activated CD4/Thy 1.2+ cells isolated from the brains of TCLi/RAG1−/− mice treated with hCLIP85:CFA was significantly greater (P<0.05) than the number of these cells isolated from the brains of mice infected with MHV only or mice that received adoptive transfer.