Table 1.

Intestinal and systemic IgA and IgG ASC and memory B-cell responses at PCD 0 and protection induced by virulent and attenuated Wa HRV in gnotobiotic pigs^a

Virus inoculation group	Mean no. ASC/5 × 105 MNC						Mean no. memory B-cells/5 ×105 MNC						Protection rate against challenge
	Intestinal lamina propia		Spleen		Bone marrow		Intestinal lamina propria		Spleen		Bone marrow		Diarrhea (%)	Shedding (%)
	IgA	IgG	IgA	IgG	IgA	IgG	IgA	IgG	IgA	IgG	IgA	IgG
Virulent Wa HRV	171	114	4	13	1	1	364	3637	58	2288	0	10	87	100
Attenuated Wa HRV 3×	8	3	2	10	0	1	8	55	135	3700	0	4	62	67
Attenuated Wa HRV 2×	6	41	1	2	NDb	ND	ND	ND	ND	ND	ND	ND	34	19

^aData summarized from Yuan et al., 1996, Yuan et al., 2001a.

^bNot determined.