Table 2.

Intestinal and systemic IgA and IgG ASC and memory B-cell responses at PCD 0 and protection induced by non-replicating vaccines in gnotobiotic pigs^a

Vaccine group	Mean no. ASC/5 ×105 MNC				Mean no. memory B-cells/5 × 105 MNC				Protection rate against challenge
	Intestinal lamina propria		Spleen		Intestinal laminar propria		Spleen		Diarrhea (%)	Shedding (%)
	IgA	IgG	IgA	IgG	IgA	IgG	IgA	IgG
Inactivated Wa HRV PO 2×	5	1	0	0	0	0	4	16	0	0
Inactivated Wa HRV+IFA IM 2×	3	4	0	34	2	0	5	2017	6	0
SA11 2/6-VLPs IN 2×	6	4	0	1	9	3	1	3	0	0
SA11 2/6-VLP+mLTIN 2× and 3×	29	16	0	1	75	149	4	26	0	10

^aData summarized from Yuan et al., 1998, Yuan et al., 2000.