Table 1.
Summary of clinical signs and faecal virus shedding in pigs after inoculation with virulent (group 1) or attenuated (group 2) PEDV and after challenge with virulent PEDV
| Group 1 | Group 2 | Group 3 | ||
|---|---|---|---|---|
| After inoculation | ||||
| Diarrhoea | Affected (%) | 33 | 5 | 0 |
| Mean duration (days) | 1.7 | 1 | 0 | |
| Virus shedding | Total (%) | 100 | 5 | 0 |
| Onset (PIDa) | 2 | 5 | – | |
| Mean duration (days) | 5.4 | 1 | 0 | |
| Maximum GMT(c) | 23.45 (a**, b**) | 1.04 | 1 | |
| After challenge | ||||
| Diarrhoea | Affected (%) | 0 | 0 | 46 |
| Mean duration (days) | 0 | 0 | 1.5 | |
| Virus shedding | Total (%) | 0 | 75 | 100 |
| Mean onset (PCDb) | – | 2 | 2.8 | |
| Mean duration (days) | 0 | 2.6 (c**) | 4.6 | |
| Maximum GMT | 1 (a*, b*) | 8.48 | 22.63 | |
Group 3 was mock inoculated and served as control at challenge. Statistically significant differences among groups are denoted by the letters: ‘a’ when differences are between groups 1 and 2, ‘b’ when differences are between groups 1 and 3 and ‘c’ for differences between groups 2 and 3. Level of significance is defined by *P≤0.5, **P≤0.01.
a
PID: postinoculation days.
b
PCD: postchallenge days.
c
GMT: geometric mean titre of antigen detected in faeces by ELISA.