Table 1.
Clinical signs, pathological lesions and agents isolated at necroscopy in individual BRSV-infected and control calves
| Calf no.a | Killed at day p.i. | Pathology (lesion) score | Fever days (p.i. days) | Maximum temperature (°C) | BRSV at necropsy | Other agents at necropsy | SAA rank | Haptoglobin rank |
| 1 | 7 | 4 | 4 (4–7) | 40.2 | Yes | Mb | 3 | 1 |
| 2 | 7 | 5 | 3 (5–7) | 40.6 | Yes | M, Pmc | 1 | 2 |
| 3 | 7 | 3 | 3 (5–7) | 40.2 | Yes | Pm | 2 | 3 |
| 4 | 7 | 2 | 2 (6–7) | 39.6 | Yes | M | 4 | 4 |
| 5 | 7 | 3 | 1 (6) | 39.6 | Yes | M | 6 | nrd |
| 6 | 7 | 3 | – | – | Yes | – | 5 | 5 |
| 7 (control) | 8 | 0 | – | – | No | M | – | – |
| 8 (control) | 8 | 1 | – | – | No | M | – | – |
| 9 (control) | 15 | 1 | – | – | No | M | – | – |
| 10 (control) | 8 | 1 | – | – | No | M | – | – |
| 11 | 6 | 4 | 2 (5–6) | 40.0 | Yes | – | 1 | 1 |
| 12 | 6 | 1 | 1 (6) | 39.5 | Yes | – | nr | nr |
| 13 | 6 | 2 | – | – | Yes | M | 3 | nr |
| 14 | 6 | 0 | – | – | Yes | – | 2 | nr |
| 15 | 15 | 4 | 9 (5–13) | 40.9 | No | M, Pae | 1 | 1 |
| 16 | 15 | 1 | 3 (5–7) | 39.5 | No | M | 2 | 2 |
a
Animals are listed according to number of fever days. If number of fever days are identical, the animal with highest lesion score is listed first. The acute phase rank is derived from the area under the acute phase response curve of the protein in question until the day of sacrifice, with 1 being the biggest area.
b
Mycoplasma dispar, Mycoplasma bovirhinis or Ureaplasma diversum.
c
P. multocida.
d
No response could be detected.
e
P. avium.