Table 1. GO and KEGG pathway enrichment analysis of DEGs in prostate cancer samples.
KEGG pathway analysis revealed that the DEGs were mainly enriched in focal adhesion and Glutathione metabolism pathway.
| Pathway ID | Term | Count | P-value |
|---|---|---|---|
| GO:0007155 | Cell adhesion | 39 | 1.86E−06 |
| GO:0007155 | Biological adhesion | 39 | 1.88E−06 |
| GO:0048762 | Mesenchymal cell differentiation | 9 | 2.52E−05 |
| GO:0014031 | Mesenchymal cell development | 9 | 2.52E−05 |
| GO:0044421 | Extracellular region part | 63 | 3.08E−14 |
| GO:0031012 | Extracellular matrix | 32 | 6.05E−11 |
| GO:0005578 | Proteinaceous extracellular matrix | 29 | 9.94E−10 |
| GO:0005578 | Extracellular region | 87 | 1.37E−09 |
| GO:0004364 | Glutathione transferase activity | 6 | 7.31E−05 |
| GO:0005201 | Extracellular matrix structural constituent | 10 | 1.57E−04 |
| hsa04510 | Focal adhesion | 17 | 4.85E−05 |
| hsa04510 | Drug metabolism | 9 | 1.64E−04 |
| hsa04510 | Glutathione metabolism | 8 | 2.54E−04 |
Note:
GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes; DEGs, differentially expressed genes.