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. 2020 Mar 31;8:e8786. doi: 10.7717/peerj.8786

Table 2. GO and KEGG pathway enrichment analysis of DEGs in the most significant module.

The genes in the most significant module were mainly enriched in the function of cell cycle phase, mitosis, cell division, microtubule cytoskeleton, spindle, p53 signaling pathway, Oocyte meiosis.

Pathway ID Term Count P-value
GO:0000279 M phase 14 6.27E−18
GO:0022403 Cell cycle phase 14 1.27E−16
GO:0007067 Mitosis 11 4.12E−14
GO:0000280 Nuclear division 11 4.12E−14
GO:0051301 Cell division 10 4.04E−11
GO:0015630 Microtubule cytoskeleton 9 1.90E−07
GO:0005819 Spindle 6 1.04E−06
GO:0051276 Chromosome organization 8 1.65E−06
GO:0044430 Cytoskeletal part 9 1.22E−05
GO:0003682 Chromatin binding 4 6.21E−04
hsa04115 p53 Signaling pathway 3 0.003543755
hsa04114 Oocyte meiosis 3 0.009071242

Note:

GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes; DEGs, differentially expressed genes.