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Summary of primary and xenograft RNA variants in acute myeloid leukemia (AML). (A) Allelic specific single nucleotide variants. Variant allele frequency (VAF) at time of diagnosis, x-axis is plotted versus the VAF in the xenograft model, y-axis. (B) Structural RNA variants. VAF at time of diagnosis, x-axis is plotted versus the VAF in the xenograft model, y-axis. PDX, patient-derived xenograft.
