Fig. 2.
Summary of primary and xenograft RNA variants in T-cell acute lymphoblastic leukemia (T-ALL). (A) Allelic specific single nucleotide variants. Variant allele frequency (VAF) at time of diagnosis, x-axis is plotted versus the variant allele frequency in the xenograft model, y-axis. (B) Structural RNA variants. VAF at time of diagnosis, x-axis is plotted versus the VAF in the xenograft model, y-axis. (C) STIL-TAL1 gene fusion identified in 2 of the T-ALL samples. PDX, patient-derived xenograft.