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. 2010 Jul 7;2010(7):CD002839. doi: 10.1002/14651858.CD002839.pub2

Comparison 2. Drug versus control in stroke: blood pressure elevation therapy.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Early death (≤ 1 month) 1 15 Odds Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
1.1 DCLHb (iv) 0 0 Odds Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
1.2 Phenylephrine (iv) 1 15 Odds Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
2 Death at end of trial 4 100 Odds Ratio (IV, Random, 95% CI) 2.96 [0.82, 10.72]
2.1 DCLHb (iv) 3 85 Odds Ratio (IV, Random, 95% CI) 2.96 [0.82, 10.72]
2.2 Phenylephrine (iv) 1 15 Odds Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
3 Death or disability at end of trial 3 85 Odds Ratio (IV, Random, 95% CI) 5.41 [1.87, 15.64]
3.1 DCLHb (iv) 3 85 Odds Ratio (IV, Random, 95% CI) 5.41 [1.87, 15.64]
3.2 Phenylephrine (iv) 0 0 Odds Ratio (IV, Random, 95% CI) 0.0 [0.0, 0.0]
4 Systolic blood pressure, early 4 100 Mean Difference (IV, Random, 95% CI) 15.82 [5.10, 26.54]
4.1 DCLHb (iv) 3 85 Mean Difference (IV, Random, 95% CI) 15.29 [3.99, 26.58]
4.2 Phenylephrine (iv) 1 15 Mean Difference (IV, Random, 95% CI) 20.60 [‐13.31, 54.51]
5 Systolic blood pressure, late 3 85 Mean Difference (IV, Random, 95% CI) 15.90 [1.84, 29.96]
5.1 DCLHb (iv) 3 85 Mean Difference (IV, Random, 95% CI) 15.90 [1.84, 29.96]
5.2 Phenylephrine (iv) 0 0 Mean Difference (IV, Random, 95% CI) 0.0 [0.0, 0.0]
6 Diastolic blood pressure, early 4 100 Mean Difference (IV, Random, 95% CI) 5.11 [‐3.18, 13.39]
6.1 DCLHb (iv) 3 85 Mean Difference (IV, Random, 95% CI) 6.01 [‐4.35, 16.38]
6.2 Phenylephrine (iv) 1 15 Mean Difference (IV, Random, 95% CI) 0.5 [‐14.86, 15.86]
7 Diastolic blood pressure, late 3 85 Mean Difference (IV, Random, 95% CI) 1.94 [‐8.96, 12.83]
7.1 DCLHb (iv) 3 85 Mean Difference (IV, Random, 95% CI) 1.94 [‐8.96, 12.83]
7.2 Phenylephrine (iv) 0 0 Mean Difference (IV, Random, 95% CI) 0.0 [0.0, 0.0]
8 Heart rate, early 3 85 Mean Difference (IV, Random, 95% CI) 0.43 [‐6.36, 7.22]
8.1 DCLHb (iv) 3 85 Mean Difference (IV, Random, 95% CI) 0.43 [‐6.36, 7.22]
8.2 Phenylephrine (iv) 0 0 Mean Difference (IV, Random, 95% CI) 0.0 [0.0, 0.0]