| Methods |
Multicentre, open randomised controlled
Separate randomisation schemes for each hospital
ITT analysis |
| Participants |
UK
55 patients: T1: 18, T2:16, C:21
Mean age: T1: 73 years, T2: 72 years, C: 70 years
Males: T1:12, T2:8, C:8
Inclusion: clinically diagnosed hemispheric strokes
Patients should be conscious and able to swallow tablets
Enrolment within 48 hours |
| Interventions |
T1: atenolol po 50 mg daily
T2: propranolol 80 mg po daily
Rx: 4 weeks |
| Outcomes |
Same time points used as Barer 1988 |
| Notes |
Same exclusions as Barer 1988 |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Adequate sequence generation? |
Low risk |
Randomisation was done in block of 3 with separate schemes for each hospital |
| Allocation concealment? |
Low risk |
Probably done |
| Blinding? |
High risk |
Open randomised controlled trial |
| Completeness of follow‐up |
Unclear risk |
Unclear from the publication |
