Cetin 2008.

Methods	Randomised controlled trial 5‐arm parallel group design Trial duration: 8 weeks  No power calculation reported
Participants	100 patients randomised 100 patients with knee OA reported at baseline Study joints: 100 knees Number of females: 100 of 100 (100%) Average age: 60 years Average BMI: 28 kg/m2
Interventions	Experimental intervention: TENS + hot packs + isokinetic exercise, 3 times per week Control intervention: hot packs + isokinetic exercise, 3 times per week Duration of treatment period: 8 weeks Analgesics allowed, unclear whether intake was similar between groups Device: MED911 Self‐administered: no Waveform: not reported Puls width: 60 msecs Pulse frequency: 60‐100 Hz Amplitude: above sensory threshold, increased to point of seeing no contraction, while patient felt comfortable Duration of stimulation per session: 20 minutes Electrodes: not reported Electrode placement: around painful areas
Outcomes	Extracted pain outcome: pain on walking after 8 weeks, described as "Knee pain severity after a 50‐m walk (VAS)" Extracted function outcome: Lequesne OA index global score after 8 weeks (Likert) No primary outcome reported
Notes	Only 2 arms qualified for inclusion in this review
Risk of bias
Bias	Authors' judgement	Support for judgement
Adequate sequence generation?	Unclear risk	No information provided
Allocation concealment?	Unclear risk	No information provided
Free of selective reporting?	Unclear risk	Trial protocol not accessible, methods section not explicit about pre‐specified outcomes
Adequate blinding of patients?	High risk	No sham intervention
Incomplete outcome reporting: intention‐to‐treat analysis performed? Pain	Unclear risk	No information provided
Incomplete outcome reporting: intention‐to‐treat analysis performed? Function	Unclear risk	No information provided
Funding by commercial organisation avoided?	Unclear risk	No information provided
Funding by non‐profit organisation?	Unclear risk	No information provided