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The figure shows the function and production of tissue plasminogen activator. (a) This figure shows the function of t-PA that it helps in degradation of blood clot by degrading fibrin by activation of plasminogen into plasmin. (b) This figure shows the production of truncated t-PA in CHO DG44 cell line. The mutated form of t-PA is resistant to inhibition by plasminogen activator inhibitor and has better effectiveness in clinical usage
