Fig. 2.2 (a).
Human sarcoma cells attacked and lysed by autologous lymphocytes. The compact small round cells are immune T cells. It appears as if the lymphocytes injected “cytolysins” into the cytoplasms. The large granular lymphoid cells in 10.21 are NK cells. (b) In 3.8, human sarcoma cells withstand attack by a mixed population of lymphocytes; some lymphocytes die apoptotic death (arrows) next to the attacked tumor cell. From the Section of Clinical Tumor Virology & Immunology, M. D. Anderson Hospital, Houston, TX, in the early 1970s [213]. Permission to re-publish is from Schenk Buchverlag, Passau and Budapest