Skip to main content
. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: Nanotoxicology. 2020 Feb 7;14(3):404–419. doi: 10.1080/17435390.2020.1717007

Table 3.

Eigenvalues (proportion of variance explained) and eigenvectors for principal components (PC) 1–6 of 31 normalized, transformed biomarker ratios, with positive (>0.10) and negative (<−0.10) loadings for each PC highlighted in red and green, respectively.

PC1 PC2 PC3 PC4 PC5 PC6
Eigenvalue 0.252 0.135 0.087 0.054 0.050 0.038
GM_CSF 0.1806 0.2986 −0.0082 −0.1514 −0.1308 0.1669
Haptoglobin −0.0103 0.0158 −0.0865 −0.2198 0.2686 −0.0016
IFN-γ 0.1971 0.2712 −0.1935 −0.0652 −0.1328 0.1277
IL-1α 0.2093 −0.1097 −0.0716 0.1074 0.1498 0.1518
IL-1β 0.2725 −0.1505 −0.1086 −0.1254 0.0327 0.1124
IL-1ra 0.2456 0.0251 −0.1024 0.1878 0.2135 −0.1045
IL-2 0.0943 0.3828 0.0809 −0.0184 −0.0830 −0.1046
IL-3 0.1638 0.1403 −0.1906 0.2698 0.0158 0.2457
IL-4 0.1381 0.3585 0.0080 −0.0044 0.0127 −0.1580
IL5 0.0955 0.3748 0.0241 −0.0011 0.0087 −0.0888
IL-6 0.2592 −0.0606 −0.1091 0.1449 −0.0740 −0.0097
IL-7 0.0701 −0.1006 −0.1721 0.4770 −0.0512 0.2287
IL-8 0.1099 −0.1930 0.2179 0.1717 −0.4130 0.0104
IL-10 0.1574 0.2512 0.0894 0.1577 0.1520 −0.1306
IL-12p40 0.2666 −0.1126 −0.1221 −0.1356 0.0154 −0.1031
IL-12p70 0.0939 0.1225 −0.3440 −0.0699 −0.3050 0.0051
IL-15 0.2616 −0.1180 0.0539 −0.1729 0.0841 −0.0782
IL-17 0.1009 0.2954 0.1286 −0.2116 −0.0303 0.3153
IL-18 0.2256 −0.0519 −0.0071 0.0866 0.2426 0.1040
IL-23 0.2527 −0.1490 −0.0557 −0.1436 0.0284 −0.0902
MIP1α 0.2107 −0.1240 0.2047 −0.1826 −0.2674 0.0448
MIP1β 0.1623 −0.0719 0.2168 0.1771 −0.3381 −0.0978
MMP9 0.2009 −0.0835 0.0379 −0.1412 −0.0229 −0.2387
MCP1 0.1226 0.0460 0.3517 0.1571 −0.0017 0.1346
SCF 0.2655 −0.1175 0.0161 −0.2352 0.0780 0.1463
TIMP1 0.0990 −0.0063 0.4512 0.0418 0.1902 −0.1643
TNFα 0.1706 −0.1097 −0.2093 0.2004 −0.2020 −0.1155
TNFβ 0.0148 0.0756 −0.2514 0.2063 0.1850 −0.4869
TNFR2 0.2140 0.0265 0.3014 0.2235 0.2017 −0.0665
VEGF 0.1480 −0.1754 −0.1230 −0.2414 0.0544 −0.1660
vWF 0.0228 −0.0768 −0.0191 0.0479 0.3267 0.4278