Figure 6. Treatment of high-risk early stage MF patients with radiation therapy is associated with increased overall survival.
(A) Kaplan-Meier estimates of overall survival in 210 patients with early-stage mycosis fungoides, according to the use of radiation therapy (brachytherapy or electron-beam therapy) in early stage patients. (B) Kaplan-Meier estimates of overall survival in 47 high-risk patients (defined as skin lesions with >25% TCF) with early-stage mycosis fungoides, according to the use of radiation therapy. Numbers at-risk are indicated at the bottom and curves were compared using the log-rank test, p<0.05 considered significant. (C) Clinical photographs of a Stage IB patient who received subsequent low-dose total skin electron beam with resultant complete remission that has remained stable over the past 3 years managed conservatively with NBUVB. (D) Clinical photographs of Stage IB patient treated with PUVA and bexarotene who then progressed to tumoral nodules and peripheral blood involvement 5 months later. This patient ultimately succumbed to her lymphoma.