Table 2.
Mean Change in Scores and Multivariable Regression-Adjusted Difference in Mean Score Change in Propensity-Matched Patients (Combined Model)
| Mean Change in Scores | Multivariable Regression-Adjusted Difference in Mean Score Change | |||||
|---|---|---|---|---|---|---|
| Change in Score (post minus pre) | P-Value | P-Value | ||||
| KCCQ Score | ARNI (n=508) Mean (SD) | no-ARNI (n=1016) Mean (SD) | ARNI vs. no-ARNI Post KCCQ Score | Difference in Mean Change Estimate (95% CI) | Covariate-Adjusted Difference in Mean Change Estimate (95% CI) | ARNI vs. no-ARNI |
| KCCQ-Overall Summary | 5.3 (18.6) | 2.5 (17.4) | <.001 | 3.2 (1.5, 4.9) | 2.9 (1.1, 4.6) | 0.001 |
| KCCQ-Physical Limitationa | 4.8 (24.8) | 2.0 (22.2) | 0.006 | 3.2 (0.9, 5.5) | 3.3 (0.8, 5.8) | 0.009 |
| KCCQ-Symptom Frequency | 4.3 (20.8) | 1.5 (21.2) | 0.004 | 2.9 (0.9, 4.9) | 2.6 (0.6, 4.6) | 0.010 |
| KCCQ-Social Limitationb | 5.9 (26.0) | 3.6 (23.8) | 0.030 | 2.6 (0.3, 5.0) | 2.7 (0.3, 5.1) | 0.029 |
| KCCQ-Quality of Life | 6.4 (23.9) | 2.7 (24.1) | <.001 | 3.8 (1.6, 6.0) | 3.3 (1.1, 5.4) | 0.003 |
a
116 sets (348 pts) omitted for missing pre- or post-match Physical Limitation score for one or more members of the set.
b
76 sets (228 pts) omitted for missing pre- or post-match Social Limitation score for one or more members of the set.