Table 3.
Patients Categorized by Pre-Post Change in KCCQ in the Combined Matched Cohort
| Pre-Post Change in KCCQ Score | ARNI (n=508) % (n) | no-ARNI (n=1016) % (n) |
|---|---|---|
| Overall Summary | ||
| Very large improvement (≥ 20) | 20.5% (104) | 12.1% (123) |
| Large improvement (10 to <20) | 12.2% (62) | 14.8% (150) |
| Moderate improvement (5 to <10) | 11.0% (56) | 12.9% (131) |
| No or small improvement or worse (< 5) | 56.3% (286) | 60.2% (612) |
| Physical Limitationa | ||
| Very large improvement (≥ 20) | 21.2% (101) | 17.4% (160) |
| Large improvement (10 to <20) | 11.1% (53) | 11.0% (101) |
| Moderate improvement (5 to <10) | 11.6% (55) | 10.4% (96) |
| No or small improvement or worse (< 5) | 56.1% (267) | 61.2% (564) |
| Symptom Frequency | ||
| Very large improvement (≥ 20) | 18.1% (92) | 15.9% (162) |
| Large improvement (10 to <20) | 13.0% (66) | 12.1% (123) |
| Moderate improvement (5 to <10) | 9.8% (50) | 8.1% (82) |
| No or small improvement or worse (< 5) | 59.1% (300) | 63.9% (649) |
| Social Limitationb | ||
| Very large improvement (≥ 20) | 23.9% (116) | 20.1% (192) |
| Large improvement (10 to <20) | 8.5% (41) | 9.1% (87) |
| Moderate improvement (5 to <10) | 9.9% (48) | 12.1% (116) |
| No or small improvement or worse (< 5) | 57.7% (280) | 58.6% (560) |
| Quality of Lifec | ||
| Very large improvement (≥ 20) | 25.6% (130) | 22.3% (227) |
| Large improvement (10 to <20) | 20.7% (105) | 16.9% (172) |
| Moderate improvement (5 to <10) | -- | — |
| No or small improvement or worse (< 5) | 53.7% (273) | 60.7% (617) |
a
116 sets (348 pts) omitted for missing pre- or post-match Physical Limitation score for one or more members of the set.
b
76 sets (228 pts) omitted for missing pre- or post-match Social Limitation score for one or more members of the set.
c
Because of the granularity of the QOL score, a “small improvement” is not possible.