Table 4.
Number Needed to Treat for Moderate and Large Thresholds of Health Status Change (Combined, ACEI/ARB, and no-ACEI/ARB Cohort)
| Cohort | NNT for ≥ Large KCCQ-OS Improvement NNT (95% CI) | NNT for ≥ Very Large KCCQ-OS Improvement NNT (95% CI) |
|---|---|---|
| Combined | 18 (10–111) | 12 (9–24) |
| ACEI/ARBa | -- | 12 (8–31) |
| no-ACEI/ARBa | -- | 13 (8–50) |
In the ACEI/ARB and No-ACEI/ARB cohorts, NNT and 95% CI for ≥moderate KCCQ-OS improvement were not calculated due to lack of statistical significance