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. Author manuscript; available in PMC: 2020 Apr 3.
Published in final edited form as: JACC Heart Fail. 2019 Sep 11;7(11):933–941. doi: 10.1016/j.jchf.2019.05.016

Table 4.

Number Needed to Treat for Moderate and Large Thresholds of Health Status Change (Combined, ACEI/ARB, and no-ACEI/ARB Cohort)

Cohort NNT for ≥ Large KCCQ-OS Improvement NNT (95% CI) NNT for ≥ Very Large KCCQ-OS Improvement NNT (95% CI)
Combined 18 (10–111) 12 (9–24)
ACEI/ARBa -- 12 (8–31)
no-ACEI/ARBa -- 13 (8–50)
a

In the ACEI/ARB and No-ACEI/ARB cohorts, NNT and 95% CI for ≥moderate KCCQ-OS improvement were not calculated due to lack of statistical significance