Fig. 13.4.

OmniBac – Universal transfer plasmids for every BEVS. (a) Acceptor plasmids pOmniBac1 and pOmniBac2 are shown schematically, functional modules are same as listed above (Fig. 13.2, bottom). These Acceptors can be combined with the Donor plasmids by Cre-LoxP recombination. (b) OmniBac plasmids comprise elements for homologous recombination as well as Tn7-based transposition. Multigene constructions based on OmniBac plasmids can therefore access all available baculovirus genomes. Thus, with the same plasmids, composite baculovirus for preclinical studies as well as manufacturing can be produced efficiently