Table 1.
Markers for Cancer Stem Cells. (Adapted from Woodward and Sulman 2008; Keysar and Jimeno 2010; Clevers 2011; Hu and Fu 2012; Sachlos et al. 2012 and other references cited in text).
| Marker | Description | Examples of tumor types |
|---|---|---|
| CD24 | Heat stable sialoglycoprotein | Ovarian cancer |
| CD34 | Hematopoietic progenitor surface glycoprotein | AML (acute myeloid leukemia) |
| CD44 | Hyaluronic acid receptor | Breast/colorectal/gastric/liver/head and neck/ovarian/pancreatic cancer |
| CD90 | Thymocyte differentiation antigen–1 (Thy-1) | Glioma/liver cancer |
| CD133 | Prominin–1 | Brain/colorectal/lung/liver/ovarian/pancreatic/prostate cancer |
| CD326 | Epithelial surface antigen (ESA) or epithelial cell adhesion molecule (EpCAM) | Colorectal/pancreatic cancer |
| ABCG2 | ATP-binding cassette drug transporter | Brain/liver/lung/ovarian/pancreatic cancer |
| ABCG5 | ATP-binding cassette drug transporter | Melanoma |
| ALDH | Aldehyde dehydrogenase | Breast/colorectal/lung/ovarian/pancreatic/prostate cancer |
| DR | Dopamine receptor | AML (acute myeloid leukemia) |