Skip to main content
. 2008;437:93–107. doi: 10.1007/978-1-59745-210-6_3

Fig. 3.7.

Fig. 3.7

Systemic and local nanoparticle delivery for siRNA therapeutics to treat ocular neovascularization. a Systemic delivery of siRNAs against VEGF pathway genes inhibits the CpG ODN-induced angiogenesis. Individual siRNAs or a mixture of total siRNAs against VEGF pathway genes were delivered with RPP nanoparticles 6 and 24 h after the CpG ODN induction. b Local delivery of siRNAs against VEGF pathway genes inhibits the CpG ODN-induced angiogenesis. Individual siRNAs or a mixture of total siRNAs against VEGF pathway genes were delivered with HKP nanoparticles 6 and 24 h after the induction