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. 2020 Apr 3;15(4):e0226396. doi: 10.1371/journal.pone.0226396

Fig 3. Elane-genotype does not substantially affect the myeloid, DC, or T cell compartments.

Fig 3

(A&B) Percentages of live CD11b+ Ly6G+ neutrophils (left panel) and CD11b+ GR1low-int F4/80+ macrophages (right panel) in the bone marrow (A) and spleens (B). (C) Percentages of live CD19- MHCII+ CD11c+ conventional dendritic cells (DCs) (left panel) and CD19- BST2+ CD11c+ plasmacytoid DCs (right panel). (D) Percentages of live CD19+ total B cells (left panel) and TCRβ+ total T cells (right panel). (E) Percentages of live TCRβ+ CD4+ T cells (left panel) and of CD4+ CD44+ CD62L- activated T cells (right panel). (F) Percentages of live TCRβ+ CD8+ T cells (left panel) and of CD8+ CD44+ CD62L- activated T cells (right panel). Bar graphs represent the mean and error bars with SEM. A two-tailed Welch’s t-test was performed to determine statistical significance within each gender. (elane-/- males n = 9; elane+/+ males n = 13; elane -/- females n = 20; elane +/+ females n = 18 mice per group unless otherwise indicated).