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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Biomaterials. 2019 Dec 26;235:119728. doi: 10.1016/j.biomaterials.2019.119728

Table 5.

Characteristics of HPMA star-like polymer conjugates with DOX

Sample Core/Pol a) Mw [kg mol−1] b) Ð Dh [nm] c) DOX [wt%] ζ-potential [mV] e)
C1 Dendrimer/P1-Prg 280 1.3 28.5±0.8 9.0 −3.3±0.9
C2 Dendron/P2-TT 360 1.2 35.4±2.3 10.0 −2.6±0.2
C3 PAMAM/P2-TT 511 1.3 40.4±5.2 10.6 −0.7±0.3
C4 PAMAM/P3-TT 220 1.7 26.0±3.3 10.1 +5.5±0.8
a)

Type of dendritic core used (Dendron = bisMPA dendron, dendrimer = bisMPA dendrimer, PAMAM = PAMAM dendrimer), Pol = polymeric precursor used for star-like polymer formulation

b)

Molecular weights and dispersity were determined by SEC using multi-angle light scattering and refractive index detectors.

c)

Hydrodynamic diameter was measured by DLS in 0.15M NaCl

e)

ζ-potential values were obtained from Malvern Zetasizer Nano ZSP