Table 2.
Antibacterial activity of BMAP-peptides against E. faecium, S. agalactiae and S. marcescens
| Organism (no. of strains) | Peptide | Range of MICa (μM) |
| E. faecium (5) | BMAP-27 | 2–16 |
| BMAP-27(1–18) | 8–>32 | |
| BMAP-28 | 1–8 | |
| BMAP-28(1–18) | 8–>32 | |
| BMAP-28(10–27) | 4–16 | |
| mBMAP-28 | 16–>32 | |
| S. agalactiae (3) | BMAP-27 | 2–4 |
| BMAP-27(1–18) | 1–4 | |
| BMAP-28 | 2–4 | |
| BMAP-28(1–18) | 2–8 | |
| BMAP-28(10–27) | 4 | |
| mBMAP-28 | 1–2 | |
| S. marcescens (3) | BMAP-27 | 1–8 |
| BMAP-27(1–18) | 4–>32 | |
| BMAP-28 | 4–16 | |
| BMAP-28(1–18) | 4–>32 | |
| BMAP-28(10–27) | 8–>32 | |
| mBMAP-28 | 0.5–>32 | |
a
MIC was defined as the lowest concentration of peptide preventing visible bacterial growth after incubation for 18h at 37°C. All the strains were grown in Mueller–Hinton broth. Results were determined with 1–2×105CFU/ml and are the mean of at least four independent experiments.