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Lineweaver–Burk plots for inhibition of substituted chalcones (1a–1j; a), chalconesemicarbazone isomers (2a–2j; b), (2a′–2j′; c) and diarylpyrazolines (3a–3j; d) on cathepsin H at fixed concentration (10−4 M) of inhibitor and varying substrate i.e. Leu βNA concentration (2.5, 2.0, 1.5, 1.0, 0.5, 0.3, 0.25 mM).
