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Detected bona fide kinase target sites are largely found hypo-phosphorylated upon kinase inhibition. Venn diagrams depicting the number of bona fide target sites of the kinase indicated (red), subset of these sites detected by phospho-proteomics (green) and subset of these exhibiting significant (pAdj < 0.05) hypo-phosphorylation (purple). Blue circles indicate a complete overlap of the two subsets.
