Metabolites altered in OA hBMSCs because of the chondrogenic differentiation process. Levels of 35 metabolites, including phospholipids, were significantly altered (p value <0.05) at day 14 when compared with day 2 of chondrogenic differentiation. DHAP, dyhidroxyacetone phosphate; PA, phosphatidic acid; CPA, cyclic phosphatidic acid; LysoPA, lysophosphatidic acid; P, phosphate; PG, phosphatidylglycerol; PI, phosphatidylinositol.