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. 2019 Apr 26;49(1):113–130. doi: 10.1093/ije/dyz078

Table 4b.

Associations of the modifiable lifestyle risk factors with age to first chronic disease among males, by chronic disease type (cause-specific cox PH models)

Characteristic Comparison group Reference group CHF
COPD
Diabetes
Lung cancer
MI
Stroke including TIA
csHR (95% CI) csHR (95% CI) csHR (95% CI) csHR (95% CI) csHR (95% CI) csHR (95% CI)
Alcohol consumption Non-drinker Light drinker 1.39 1.05, 1.84 1.10 0.96, 1.27 1.17 1.06, 1.29 1.10 0.67, 1.80 1.51 1.16, 1.95 0.84 0.66, 1.07
Moderate drinker 0.85 0.62, 1.16 1.01 0.88, 1.17 0.97 0.87, 1.08 1.00 0.59, 1.68 1.11 0.84, 1.46 0.80 0.62, 1.02
Heavy drinker 1.27 0.84, 1.92 0.89 0.74, 1.06 0.72 0.62, 0.84 1.10 0.59, 2.02 0.95 0.67, 1.36 1.01 0.72, 1.41
BMI Underweight Healthy weight 1.43 0.42, 4.82 1.71 1.15, 2.54 1.55 0.98, 2.46 1.96 0.59, 6.52 0.00 0.00, 99.99 1.32 0.43, 40.00
Overweight 1.01 0.79, 1.29 0.88 0.79, 0.97 1.83 1.64, 2.03 0.63 0.44, 0.91 1.08 0.87, 1.33 0.92 0.75, 1.14
Obese, class 1 1.46 1.08, 1.98 0.85 0.73, 0.98 3.68 3.28, 4.12 0.55 0.32, 0.96 1.40 1.08, 1.81 0.77 0.57, 1.03
Obese, class 2 2.08 1.31, 3.31 0.81 0.62, 1.05 6.03 5.22, 6.97 0.54 0.18, 1.62 1.18 0.75, 1.86 1.44 0.94, 2.20
Obese, class 3 1.78 0.73, 4.33 0.76 0.47, 1.25 8.95 7.4, 10.82 0.49 0.05, 5.05 1.30 0.57, 2.97 1.24 0.54, 2.87
Unknown BMI 1.39 0.99, 1.96 1.08 0.84, 1.38 2.16 1.71, 2.73 0.73 0.34, 1.54 1.17 0.75, 1.81 1.12 0.78, 1.60
Cigarette smoking Heavy smoker Never smoked 0.99 0.57, 1.72 7.99 6.75, 9.46 1.09 0.92, 1.30 38.60 18.7, 79.7 5.29 3.84, 7.28 1.27 0.84, 1.93
Light smoker 1.16 0.84, 1.59 5.52 4.81, 6.33 1.01 0.91, 1.12 15.40 7.88, 29.9 3.37 2.63, 4.31 1.03 0.79, 1.35
Former heavy smoker 1.12 0.83, 1.50 1.91 1.58, 2.31 1.09 0.97, 1.23 7.41 3.57, 15.4 1.44 1.06, 1.96 1.02 0.78, 1.33
Former light smoker 0.96 0.75, 1.23 1.62 1.38, 1.91 0.95 0.86, 1.04 4.01 1.96, 8.22 1.75 1.37, 2.23 0.69 0.54, 0.88
Former smoker, amount unknown 1.04 0.65, 1.65 0.90 0.61, 1.32 1.01 0.84, 1.21 2.59 0.73, 9.15 0.80 0.43, 1.49 0.74 0.46, 1.20
Daily fruit and vegetable consumption 0 to 3 times 6 or more times 1.02 0.75, 1.39 1.12 0.95, 1.32 1.13 1.01, 1.27 1.16 0.64, 2.09 1.03 0.78, 1.36 0.87 0.66, 1.14
3 to 6 times 0.98 0.74, 1.30 1.09 0.93, 1.28 1.04 0.93, 1.15 1.16 0.65, 2.06 1.00 0.77, 1.30 1.00 0.78, 1.28
Leisure physical activity Moderately active Active 0.75 0.57, 0.99 0.89 0.77, 1.03 1.06 0.95, 1.17 1.81 1.06, 3.08 1.28 1/00, 1.62 0.88 0.69, 1.11
Slightly active 0.91 0.71, 1.16 1.20 1.06, 1.36 1.16 1.05, 1.27 1.70 1.03, 2.83 0.98 0.77, 1.24 0.90 0.72, 1.12
No physical activity 1.11 0.79, 1.58 1.31 1.11, 1.54 1.18 1.03, 1.35 1.81 0.96, 3.41 1.32 0.96, 1.80 1.02 0.73, 1.43

Models have also been adjusted for: ethnicity, immigrant status, rural residence, education level, income, marital status, self-rated health, life stress, asthma and high blood pressure.