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. 2019 May 16;49(1):301–311. doi: 10.1093/ije/dyz098

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© The Author(s) 2019. Published by Oxford University Press on behalf of the International Epidemiological Association.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — The proportion of pre-term pre-eclampsia cases (95% confidence interval) by the quintile of 4-hydroxyglutamate and C-glycosyltryptophan at 12, 20 and 28 wkGA. (A) 4-hydroxyglutamate at 12 wkGA; (B) C-glycosyltryptophan at 12 wkGA; (C) 4-hydroxyglutamate at 20 wkGA; (D) C-glycosyltryptophan at 20 wkGA; (E) 4-hydroxyglutamate at 28 wkGA; (F) C-glycosyltryptophan at 28 wkGA. The non-cases were weighted by the inverse of the random sub-cohort sampling fraction (= 12.85) to obtain the proportion of cases of pre-term pre-eclampsia. There were no cases in the first quintile of 4-hydroxyglutamate at 20 wkGA and therefore the 95% confidence interval could not be calculated. Two-sided logistic-regression P-values are given for the linear trend between the quintile and log-odds of pre-term pre-eclampsia. PE, pre-eclampsia; wkGA, weeks of gestational age.