Figure 1.

The incidence of severe sepsis-associated acute kidney injury (AKI) on Day 3, renal replacement therapy (RRT) use, and renal recovery from early AKI according to the updated Pediatric Sepsis Biomarker Risk Model (PERSEVERE-II) risk category. The cohort was grouped into one of three PERSEVERE-II risk categories: low risk (mortality risk, 0.000–0.019), intermediate risk (mortality risk, 0.167–0.189), and high risk (mortality risk, 0.300–0.571). (A) Proportion of patients with severe sepsis-associated AKI on Day 3 (P < 0.001, χ², 2 degrees of freedom [df ]). (B) Proportion of patients requiring RRT (P < 0.001, χ², 2 df ). (C) Proportion of patients with renal recovery by Day 3 of septic shock (P = 0.039, χ², 2 df ).