Table 3.
Diagnostic performance of a reference freeze-dried direct agglutination test modified by incorporating citrate-saline/formaldehyde as an antigen diluent for the detection of VL in the human (VL) and CVL hosts
| Origin of blood/serum sample | Final diagnosis | Titers expressed as the number of the 2-fold serial dilution* ≤ 2 3 4 5 6† 7 8 ≥ 9 | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Human (48) | VL (21) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 21 |
| Non-VL (27) | 9 | 1 | 14 | 3 | 0 | 0 | 0 | 0 | |
| Canine (43) | CVL (10) | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 6 |
| Non-CVL (33) | 29 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | |
CVL = canine visceral leishmaniasis; VL = visceral leishmaniasis.
* Titers are expressed as the number of 2-fold serial dilution starting from 1:100 (dilution 1) up to 1:25,600 (dilution 9).
† Cutoff titer for VL and CVL = 1:3,200 (dilution 6).