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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Clin Cancer Res. 2019 Dec 23;26(7):1624–1632. doi: 10.1158/1078-0432.CCR-19-3165

Table 2.

Prevalence of TRK Fusions Overall and by Cancer Type.

Histology Percent 95% CI Fraction
Overall 0.28% [0.22% - 0.35%] 74/26312
Salivary Carcinoma 5.29% [2.76% - 9.05%] 12/227
Thyroid Cancer 2.22% [1.07% - 4.04%] 10/451
Sarcoma NOS 1.17% [0.54% - 2.21%] 9/770
Uterine Sarcoma 1.15% [0.14% - 4.09%] 2/174
Glioblastoma Multiforme 0.62% [0.17% - 1.59%] 4/641
Appendiceal Adenocarcinoma 0.57% [0.01% - 3.12%] 1/176
Melanoma 0.54% [0.17% - 1.25%] 5/932
Biliary Tract Cancer 0.36% [0.04% - 1.30%] 2/553
Unknown Primary 0.31% [0.01% - 1.74%] 1/318
Colon Cancer 0.35% [0.15% - 0.68%] 8/2306
Pancreatic Cancer 0.30% [0.08% - 0.78%] 4/1315
Lung Adenocarcinoma 0.16% [0.06% - 0.36%] 6/3658
Invasive Breast Carcinoma* 0.08% [0.02% - 0.23%] 3/3775
*

Excludes Secretory Breast Cancer