Table 3.

Binary logistic mixed models estimating explained variance in heavy drinking and at least monthly RSOD at country and regional levels (OR, 95%CI). M0: two-level models estimating variance explained by country differences, M1: three-level models estimating variance explained at the country and the regional level, ICC (95%CI), separate models for men and women

	Heavy drinking			At least monthly RSOD
	total	men	women	total	men	women
N individuals	105,061	47,393	57,668	84,008	37,881	46,127
N countries	23	23	23	21	21	21
N regions	132	132	132	115	115	115
M0 (2- level model; country level variation)
Age (in decades), OR (95%CI)	1.09 (0.93–1.27)	1.10 (0.94–1.30)	1.06 (0.92–1.23)	0.72 (0.66–0.79)	0.75 (0.69–0.82)	0.64 (0.59–0.70)
Gender (males), OR (95%CI)	1.92 (1.53–2.41)	--	--	5.03 (3.93–6.43)	--	--
ICC (country) 95% CI	0.13 (0.09–0.18)	0.10 (0.05–0.18)	0.32 (0.21–0.45)	0.16 (0.10–0.26)	0.14 (0.08–0.22)	0.32 (0.17–0.52)
M1 (3-level model: country and regional variation measured by ICC)
Age (in decades), OR (95%CI)	1.09 (0.93–1.27)	1.11 (0.94–1.30)	1.06 (0.91–1.24)	0.72 (0.66–0.78)	0.75 (0.68–0.82)	0.64 (0.58–0.69)
Gender (males), OR (95%CI)	1.93 (1.54–2.42)	--		5.09 (3.97–6.53)	--
ICC (country) 95%CI	0.13 (0.09–0.17)	0.10 (0.05–0.19)	0.31 (0.21–0.44)	0.16 (0.10–0.24)	0.14 (0.08–0.22)	0.30 (0.16–0.51)
ICC (region) 95%CI	0.02 (0.009–0.05)	0.02 (0.016–0.04)	0.02 (0.01–0.05)	0.02 (0.01–0.04)	0.02 (0.01–0.03)	0.04 (0.02–0.07)