Figure 3.

GFI-1b, ITGAM and KCTD12 gene expression induction in NB4 cells by selected 1–3 derivatives. The inhibitors were tested at their biochemical anti-LSD1 IC₅₀ values (see Table 1). Fold-inductions were calculated with respect to DMSO, which was used as a control. Data for GFI-1b and ITGAM gene induction by 3b, 3f and 3g have been reported in ref. ^[14] and added here for comparison.