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. 2020 Apr 3;10:5913. doi: 10.1038/s41598-020-62699-0

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Changes in gene expression in NPY-KO zebrafish under acute stress. (A) orx mRNA level. (B) cck mRNA level. (C) crh mRNA level. (D) pomc mRNA level. (E) ist mRNA level. (F) gr mRNA level. (G) mr mRNA level. (H) avp mRNA level. (I) th1 mRNA level. (J) th2 mRNA level. Each gene expression level in NPY-KO zebrafish is relative to the value in wild-type fish. N = 15. Results are shown as means ± standard errors of three independent experiments. *p < 0.05, **p < 0.01. n.s., not significant.