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. 2020 Apr 3;10:5869. doi: 10.1038/s41598-020-62648-x

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Aspirin treated mice with breast cancer have altered gene expression in vivo. Gene expression was determined via RT-qPCR of MDA-MB-231-LM2 breast cancer tumours harvested from mice treated without and with aspirin at experimental end. Scatter dot plot showing the mRNA gene expression of eight VM-associated genes; CDH5, EPHA2, KDR, and LAMC2, MMP1, MMP2, MMP9, and MMP14 normalised to housekeeping genes (GAPDH, ACTB, and CYCA). Blue lines in the graph represent the median values, *p < 0.05, Mann-Whitney U test.