Table 1.
Top 20 immunogenic CTL peptide candidates with scores were generated from a prediction tool, NetMHC.
| Rank-ing | Gene | Eluted Peptide | IC50 (nM) | Immuno-genicity score | HLA type | Rank-ing | Gene | Eluted Peptide | IC50 (nM) | Immuno-genicity score | HLA type |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | DYNLRB1 | SLMHSFILK | 5 | 0.030 | A11:01 | 11 | LDHA | GSLFLRTPK | 12 | 0.178 | A11:01 |
| 2 | PRKDC | STFDTQITK | 6 | 0.124 | A11:01 | 12 | PRKDC | STFDTQITKK | 12 | 0.017 | A11:01 |
| 3 | NDUFC2 | KTYGEIFEK | 8 | 0.413 | A11:01 | 13 | PSMD14 | AAMLDTVVFK | 12 | 0.133 | A11:01 |
| 4 | EIF4A1 | GIYAYGFEK | 8 | 0.224 | A11:01 | 14 | LDHB | GSLFLQTPK | 14 | 0.021 | A11:01 |
| 5 | PSMD14 | AMLDTVVFK | 8 | 0.199 | A11:01 | 15 | AURKB | KSHFIVALK | 14 | 0.323 | A11:01 |
| 6 | DHCR7 | AVSTFAMVK | 9 | 0.012 | A11:01 | 16 | BCAP31 | GAMEHFHMK | 14 | 0.110 | A11:01 |
| 7 | TOMM5 | RVTPFILKK | 9 | 0.105 | A11:01 | 17 | RPL24 | ASLADIMAK | 15 | 0.057 | A11:01 |
| 8 | ROPN1B | SALGVTITK | 10 | 0.242 | A11:01 | 18 | EIF3H | STYYGSFVTR | 19 | 0.035 | A11:01 |
| 9 | TUBB | STAIQELFK | 11 | 0.187 | A11:01 | 19 | NDUFA11 | GTFLEGVAK | 19 | 0.214 | A11:01 |
| 10 | TCP1 | GVFEPTIVK | 11 | 0.301 | A11:01 | 20 | C3 | ATFGTQVVEK | 19 | 0.129 | A11:01 |